1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13735AR
    Quinacrine dihydrochloride (Standard)
    Inhibitor
    Quinacrine (dihydrochloride) (Standard) is the analytical standard of Quinacrine (dihydrochloride). This product is intended for research and analytical applications. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis.
    Quinacrine dihydrochloride (Standard)
  • HY-W774926
    Permethrin-d6
    Inhibitor
    Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes).
    Permethrin-d<sub>6</sub>
  • HY-N7236
    Pervicoside B
    Inhibitor
    Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases.
    Pervicoside B
  • HY-135625
    BPH-1218
    BPH-1218 is an inhibitor of squalene synthase (SQS), with the IC50 of 31 nM and 64 nM for TcSQS and HsSQS, respectively, that can be used as an anti-infective agent.
    BPH-1218
  • HY-173051
    Antiparasitic agent-24
    Inhibitor
    Antiparasitic agent-24 (Compound 14a) is an antiparasitic agent, with EC50s of 0.005 μM (L. maj), 0.069 μM (L. don), 0.82 μM (T. brucei), 4.1 μM (T. cruzi) respectively.
    Antiparasitic agent-24
  • HY-15311R
    Avermectin B1 (Standard)
    Inhibitor
    Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy.
    Avermectin B1 (Standard)
  • HY-182347
    LSPN954
    Inhibitor
    LSPN954 is an indole-based peptidomimetic antiplasmodial agent. LSPN954 shows slow-acting inhibitory activity, allowing the initial development of Plasmodium followed by morphological changes. LSPN954 can be used in malaria research.
    LSPN954
  • HY-118606
    LDN-0044878
    Inhibitor
    LDN-0044878 is a PAK3 inhibitor. LDN-0044878 inhibits the proliferation or induces the death of p53-deficient cells. LDN-0044878 exhibits moderate trypanocidal activity against Trypanosoma brucei, but does not directly inhibit the core target Rhodesain. LDN-0044878 can be used in studies related to cervical adenocarcinoma and Trypanosoma brucei infection.
    LDN-0044878
  • HY-121768
    Trimethacarb
    Trimethacarb is a type of insecticide used for pest control.
    Trimethacarb
  • HY-180156
    FM-8007
    Inhibitor
    FM-8007 is a potent acaricide. FM-8007 exhibits broad-spectrum efficacy against Tetranychus cinnabarinus, with LC50 values of 1.1 mg/L for adults, 0.25 mg/L for larvae, and 0.85 mg/L for eggs. FM-8007 also provides sustained field control against Panonychus citri. FM-8007 can be used for integrated pest management (IPM).
    FM-8007
  • HY-148269
    AN13762
    Inhibitor
    AN13762 is a benzoxaborole antimalarial agent. AN13762 augments Plasmodium falciparum stress responses. AN13762 acts against cultured and fresh Plasmodium falciparum isolates and in vivo murine malaria models. AN13762 can be used for the research of malaria.
    AN13762
  • HY-B2157R
    Robenidine hydrochloride (Standard)
    Inhibitor
    Robenidine hydrochloride (Standard) is the analytical standard of Robenidine hydrochloride. This product is intended for research and analytical applications. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.
    Robenidine hydrochloride (Standard)
  • HY-W011517R
    2-Fluoroadenosine (Standard)
    Inhibitor
    2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions.
    2-Fluoroadenosine (Standard)
  • HY-N15095
    Aplasmomycin
    Inhibitor
    Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo.
    Aplasmomycin
  • HY-B1896AR
    Piperaquine phosphate (Standard)
    Inhibitor
    Piperaquine (phosphate) (Standard) is the analytical standard of Piperaquine (phosphate). This product is intended for research and analytical applications. Piperaquine phosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin.
    Piperaquine phosphate (Standard)
  • HY-76204S
    Glycine ethyl ester-13C hydrochloride
    Inhibitor
    Glycine ethyl ester-13C hydrochloride is a 13C-labeled Glycine ethyl ester hydrochloride (HY-76204). Glycine ethyl ester monohydrochloride is a Glycine (HY-Y0966) derivative.
    Glycine ethyl ester-<sup>13</sup>C hydrochloride
  • HY-N2932
    β-Yohimbine
    Inhibitor
    β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL).
    β-Yohimbine
  • HY-B1881S
    Pirimiphos-methyl-d6
    Inhibitor
    Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl (HY-B1881). Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
    Pirimiphos-methyl-d<sub>6</sub>
  • HY-136394R
    Diafenthiuron (Standard)
    Inhibitor
    Diafenthiuron (Standard) is the analytical standard of Diafenthiuron. This product is intended for research and analytical applications. Diafenthiuron is a thiourea compound commonly used pesticide. Diafenthiuron inhibits mitochondrial functioning in insect pests.
    Diafenthiuron (Standard)
  • HY-N4037
    Homopterocarpin
    Inhibitor
    Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective, antioxidant and antiplasmodial activity. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC50 and a Ki of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress.
    Homopterocarpin

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